Albinterferon
WebAlbinterferon alpha-2b: a genetic fusion protein for the treatment of chronic hepatitis C. Treatment regimens based on the use of interferon-alpha (IFN-alpha) remain the … WebMay 9, 2008 · Albinterferon alfa-2b (alb-IFN) is an 85.7-kDa protein consisting of recombinant human IFNα-2b genetically fused to recombinant human albumin. In vitro …
Albinterferon
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WebDec 7, 2007 · Albinterferon α-2b activates the ISRE pathway, demonstrating IFN-stimulated gene (ISG) induction characteristics similar to PEG-IFN-α-2a 4. RLU, relative … WebJun 30, 2024 · What is interferon alfa-2b? Interferon alfa-2b is used to treat hairy cell leukemia, malignant melanoma, follicular lymphoma, Kaposi's sarcoma caused by AIDS, and certain types of genital warts. Interferon alfa-2b is also used to treat chronic hepatitis B or C in adults, and to treat chronic hepatitis B in children who are at least 1 year old.
WebThe albumin-fusion platform takes advantage of the long half-life of human albumin to provide a new treatment approach that allows the dosing frequency of IFN-α to be reduced in individuals with chronic hepatitis C. Albinterferon α-2b (alb-IFN), a recombinant polypeptide composed of IFN-α2b genetically fused to human albumin, has an extended … WebJul 30, 2008 · Albinterferon Alfa 2b Single Dose in Japanese Chronic Hepatitis C Patients The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. ClinicalTrials.gov Identifier: …
WebMay 9, 2008 · Albinterferon alfa-2b (alb-IFN) is an 85.7-kDa protein consisting of recombinant human IFNα-2b genetically fused to recombinant human albumin. This is the first report of the efficacy, safety, and patient-reported HRQOL of alb-IFN administered every 2 or 4 weeks compared with PEG-IFNα-2a, all in combination with RBV, in previously … WebAug 1, 2012 · Controlling aggregation in protein therapeutics is a significant challenge. In this study, the aggregation behavior of albinterferon-α 2b, a genetic fusion protein combining human serum albumin and α-interferon, was examined as a function of solution conditions. The stability was monitored during agitation and during storage at elevated temperature, …
WebMay 4, 2024 · Alpha interferon is a cytokine produced by the innate immune system in response to environmental exposures including viral infections. Alpha interferon in various formulations has been developed as therapy …
WebNov 25, 2009 · Brand name: Zalbin. Generic name: albinterferon alfa-2b. Company: Human Genome Sciences, Inc. Treatment for: Hepatitis C. Zalbin (albinterferon alfa-2b) … thor motor coach miramar class aWebAug 1, 2012 · Controlling aggregation in protein therapeutics is a significant challenge. In this study, the aggregation behavior of albinterferon‐α2b, a genetic fusion protein combining human serum albumin and α‐interferon, was examined as a function of solution conditions. The stability was monitored during agitation and during storage at elevated temperature, … thor motor coach miramar 37.1 for saleAlbinterferon (alb-IFN, trade name Albuferon) is a recombinant fusion protein drug consisting of interferon alpha (IFN-α) linked to human albumin. Conjugation to human albumin prolongs the half-life of the IFN-α to about 6 days, allowing to dose it every two to four weeks. umhb football game score todayWeb154 rows · Nov 18, 2007 · Albumin-interferon alpha (Albuferon) is a novel, long-acting form of interferon alpha. Recombinant interferon alpha is approved for the treatment of … umhb football tickets 2018http://hivandhepatitis.com/hep_c/news/2009/120809_a.html umhb football tickets for saleWebJun 21, 2007 · Patients will receive Albinterferon alfa-2b at a dose of 900 mcg every 2 weeks for 48 weeks, by injection under the skin. Ribavirin is given at 1,000 mg or 1,200 … thor motor coach omni bt36WebJul 1, 2014 · Background and AimsAlbinterferon is a fusion of albumin and interferon alfa-2b developed to improve the pharmacokinetics, convenience, and potential efficacy of interferon-α for the treatment of... thor motor coach omni xg32