WebJul 1, 2024 · In this study, lncRNA-LOC is significantly downregulated in HCC and negatively correlated with overall survival in HCC patients. LncRNA-LOC is negatively regulated by Ct-HBx in vitro and in vivo (HCC specimens). Two novel transcripts of LncRNA-LOC in HepG2 and Huh7 cell lines were identified by 5’ and 3’ rapid amplification of cDNA ends ... WebJul 26, 2024 · D Re-introduction of TXNIP into Ct-HBx- (HBx-120, HBx-134) expressing cells was confirmed at the protein and genomic level by western blotting and qRT-PCR.
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WebEctopic expression of M3-HBx and Ct-HBx significantly increased proliferation and S phase proportion of HepG2 and HeLa cells, compared to WT-HBx. Plasminogen activator inhibitor-1 (PAI1) and... WebSep 3, 2013 · Ct-HBx expression in adjacent hepatic tissues significantly predicted an unfavorable RFS in the antiviral group (P < .001). Conclusion. Although it might not affect the HCC-promoting potential of Ct-HBx, NA treatment is effective in normalizing liver function, decreasing HBV-HCC recurrence, and improving postoperative survival. This … ionbond 42
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WebFeb 11, 2024 · The most common HBV X gene encoding Ct-HBX in HBV-HCC samples significantly increased the aggressiveness of HCC compared with the full-length X gene [84]. A team of researchers injected wild-type ... WebMay 6, 2024 · Ct-HBx could downregulate Txnip via the transcriptional repressor, nuclear factor of activated T cells 2 (NFACT2) . Mutations in the Txnip gene are also detected in 7% of patients with bladder cancer ( 19 ), although the role of … WebJul 1, 2024 · In this study, lncRNA-LOC is significantly downregulated in HCC and negatively correlated with overall survival in HCC patients. LncRNA-LOC is negatively regulated by … ontario health and safety representative