Thz1 ic50
WebbTHZ531 is a covalent inhibitor of both CDK12(IC50=158 nM) and CDK13(IC50=69 nM). Home Tools. Log in. Products Inhibitors Libraries Kits Services Contact Us. Cart ... WebbTHZ-1 (CDK7 inhibitor) Catalog No. : PC-46008 Not For Human Use, Lab Use Only. A potent, selective, covalent CDK7 inhibitor with IC50 of 3.2 nM. Get Quotation Now * Please …
Thz1 ic50
Did you know?
WebbYKL-5-124,CAS:1957203-01-8.YKL-5-124 is a novel potent, selective, and covalent CDK7 inhibitor (IC50=53.5 nM), inhibits CDK7/CycH/MAT1 enzymatic activity with IC50 of 9.7 nM.Quality confirmed by NMR,HPLC & MS. Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists. WebbTHZ1 is a covalent inhibitor of CDK7 with IC50 value of 3.2nM [1]. THZ1 covalently modifies CDK7 by targeting C312 residue outside of the kinase domain, providing an …
WebbFor research use only. THZ2, a THZ1 analog, is a selective inhibitor of CDK7 with IC50 of 13.9 nM. THZ2 efficiently suppresses the clonogenic growth of TNBC cells with IC50 of ~10 nM. CAS No. 1604810-84-5 Purity … WebbTHZ2, an analogue of THZ1 with improved pharmacokinetic features, is a potent, selective CDK7 inhibitor with IC50 of 13.9 nM, displays a 5-fold improved half-life in vivo compared with THZ1; selectively targets CDK7 and potently inhibits the growth of triple-negative but not ER/PR+ breast cancer cells, efficiently suppresses the clonogenic growth of TNBC …
Webbbio-THZ1 is the biotinylated analog of THZ1 which is a covalent/irreversible CDK7 inhibitor (IC50: 3.2 nM). References: Targeting transcription regulation in cancer with a covalent … WebbTH-Z835,CAS 2766209-50-9, THZ 835, KRAS G12D inhibitor. TH-Z835 is a potent, mutant selective KRAS (G12D) inhibitor with IC50 of 1.6 uM.
WebbTHZ-1 (CDK7 inhibitor) Catalog No. : PC-46008 Not For Human Use, Lab Use Only. A potent, selective, covalent CDK7 inhibitor with IC50 of 3.2 nM. Get Quotation Now * Please select Quantity before adding items. or Bulk Inquiry Bulk size, bulk discount! E-mail: [email protected] Tech Support: [email protected]
WebbTHZ1 is a novel selective and potent covalent CDK7 inhibitor with IC50 (binding affinity) of 3.2 nM; inhibits Jurkat cell's proliferation with IC50 of 50 nM Availability: In stock Free … dysphagia head turn to weak sideWebbbio-THZ1,CAS:1604811-14-4.bio-THZ1 is a biotinylated version of THZ1 and binds irreversibly to CDK7..Quality confirmed by NMR,HPLC & MS. Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists. Find Your Distributors Select Your Country or Region. Australia. Austria. Belgium. Brazil. Canada. … c# set property asyncWebb6 apr. 2024 · THZ1 Arrests the Cell Cycle of B-ALL Cell Lines in vitro To investigate the anti-proliferative effect of CDK7 inhibitor on the B-ALL cells, we first determined the CDK7 … dysphagia in alcoholicsWebb公告提醒：爱必信所有产品和服务仅用于科学研究，不用于临床应用及其他用途提供产品和服务（也不为任何个人提供产品和服务）! 抑制剂描述： 产品名称：BMS-1166 产品别名：见爱必信官网 英文别名：BMS-1166 靶点：PD-1/PD-L1 CAS：1818314-88-3 纯度 c# set property by nameWebb8 maj 2024 · The first CDK inhibitor to enter clinical trial was the semi-synthetic flavone derivative, alvocidib (flavopiridol; Fig. 3a ), which inhibits CDK1, 2, 4, 6, 7 and 9 (Table 2) [ 87, 88, 89, 90 ]. Between 2008 and 2014, alvocidib was evaluated in more than 60 clinical trials for numerous tumour types [ 91 ]. cset primary schoolWebb1 sep. 2015 · In three independent patient-derived TNBC cultures, THZ1 effectively reduced cell viability (IC50 < 100 nM) ( Figure 1E ). Consistent with our findings obtained from … c# set properties when creating objectWebbTHZ1是一种新型的选择性强效共价CDK7抑制剂，IC50（结合亲和力）为3.2 nM。 抑制Jurkat细胞的增殖，IC50为50 nM。 库存： 现货 添加到购物车 获取免费样品 大包装询价 或 添加到收藏 产品仅用于科学研究，不针对患者销售，望谅解. 顾客使用 Adooq 产品发表的高质量科研文献 prev next 产品详情 产品资料 产品标签 Product Questions 生物活性 THZ1 … dysphagia in alzheimer\u0027s patients